1969. Dr. Malcolm Sayer is hired as a clinical physician at a psychiatric hospital in the Bronx, despite he only having a research background. The job is not ideal on his side as he has difficulties relating to people which is the reason he has focused on research projects not involving human subjects, while the hospital hires him somewhat out of desperation in not finding anyone else with the qualifications who wants the job. Most of his patients are in a semi-catatonic state and are housed in what some of the orderlies coin the "garden" ward, where all they can do for the patients is water and feed them. He notices that some of the patients, despite their generally catatonic state, respond in unusual ways to certain stimuli. In doing some research, he also finds that some common bonds between these patients are that they suffered from encephalitis in the 1920s or 1930s, and that their physical states are like they have Parkinson's disease frozen in time. As such, he is able to ...Written by
Penny Marshall at first wanted Bill Murray to play Leonard Lowe, who was interested in the project, but she decided against it because she didn't want audiences expecting a comedy. See more »
At one point Dr. Sayers describes L-DOPA as synthetic dopamine. It is in fact a precursor to dopamine, i.e. a substance used by the body to synthesize dopamine. See more »
What we do know is that, as the chemical window closed, another awakening took place; that the human spirit is more powerful than any drug - and THAT is what needs to be nourished: with work, play, friendship, family. THESE are the things that matter. This is what we'd forgotten - the simplest things.
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Here's a good example of how you can still make a great modern-day movie without profanity, violence or sex.
This is an amazing story, based on fact, about about a doctor who makes great progress fighting an illness that heretofore was considered incurable. These were patients in catatonic states, and the good doctor uses an experimental drug to snap these people back to reality and to a normal life as they once had. The patients, and how they react, both before and after the medications, is really fascinating.
Robert De Niro is outstanding as one of the patients, but that's not a surprise knowing all the fine acting performances he's done over the years. Robin Williams, relatively new to dramatic acting when this came out, was also excellent in a very low-key role. Penelope Ann Miller is extremely sweet and appealing. I wish both she and Williams would do more roles like that.
With multiple viewings, I came to appreciate the minor characters in here a lot more, such as De Niro's mother, played by Ruth Nelson, whom I fondly remember in the 1945 film "A Tree Grows In Brooklyn." What a treat is was to see her again and this was just two years before she died. Also, Alice Drummund as the patient known as "Lucy" was notable.
Language-wise, i's almost stunning to watch a movie which has De Niro, Williams, Miller and John Heard and not hear one profane word uttered! (The film isn't perfect, however, as some idiot decided to insert one f-word, and in a totally unnecessary circumstance.)
This is a memorable story and one I guarantee you won't forget because the subject matter is so different.
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