Georgette (Burnett) is a woman attending the 30th reunion at her high school, where before her sex-change operation she had been "George", the quarterback on the football team. Swoosie Kurtz plays "George's" ex-girlfriend from school.
Dr. Elaine Daniels (Burnett) learns that her ex-husband/co-worker, Dr. Arthur Daniels (Alex Rocco), is dating a younger woman and to make him jealous, she flaunts a much younger man under Arthur's nose.
Myna is a devout churchgoer who needs to raise $25,000 to save her church. One day she meets Steve, who she believes is an angel who will answer her prayers and help her save her church. He takes her to Atlantic City to convince her to win the $25,000 by gambling, but she soon learns that everything is not as it seems.
Lillian Preskin (Burnett) is a frisky 82-year-old senior citizen who still has an eye for the gentlemen at her nursing home, much to the consternation of her daughter (Fay) who threatens to send her mother to a home run by nuns if she engages once more in sex with the residents.
Evelyn Sweets (Burnett) is featured in two separate episodes about her "Chapel of Romance": Evelyn is approached by a woman with a ventriloquist's dummy who pleads with her to marry them in "Dummy Dearest"; Evelyn is approached by Chester Neff, who assumes that her ad's tag I'll marry anyone means that she will become his wife in "Being Out There".