| Cast overview, first billed only: | |||
| Meryl Streep | ... | Mary Fisher | |
| Roseanne Barr | ... | Ruth Patchett | |
| Ed Begley Jr. | ... | Bob | |
| Linda Hunt | ... | Hooper | |
| Sylvia Miles | ... | Mrs. Fisher | |
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Elisebeth Peters | ... | Nicolette Patchett |
| Bryan Larkin | ... | Andy Patchett | |
| A Martinez | ... | Garcia | |
| Maria Pitillo | ... | Olivia Honey | |
| Mary Louise Wilson | ... | Mrs. Trumper | |
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Susan Willis | ... | Ute |
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Jack Gilpin | ... | Larry |
| Robin Leach | ... | Himself | |
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Nitchie Barrett | ... | Bob's Secretary |
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June Gable | ... | Realtor |
Ruth is a wife and mother who tries to please her husband (Bob) but finds him pulling away and spending more time at the office than at home. When he begins an affair with a famous romance novelist (Mary) and leaves Ruth to raise their kids, she decides she's had enough of playing nice docile housewife. Ruth endeavors to show Bob and Mary the truth about themselves and each other, while creating a new successful life of her own. Written by Mia Holder
Meryl Streep (Mary Fisher), "Out of Africa",'85 put her heart and soul into this role and proved to her many fans that she is a great actress who can even play comedy and make it work. Roseanne Barr(Ruth Patchett), "Blue in the Face",'95, performs as an ugly housewife who is abused beyond words by Bob, her husband, (Ed Begley,Jr.),"Auto Focus",'02. Bob plays a horrible husband who deserves just what he gets from the SHE-DEVIL! If you love Meryl Streep and Roseanne, just sit back and enjoy this CRAZY film and forget about your troubles.