Although Dave Grusin recorded the songs for the movie soundtrack, Beau Bridges and Jeff Bridges both learned to play all the songs in the film. To make their playing appear realistic, the actors watched videotapes of Grusin's hands playing the music.
Michelle Pfeiffer's debut performance with the Baker Boys (in which she sings "Ten Cents A Dance") takes place in the Cloud Room, on the top floor of Seattle's Camlin Hotel. Opened in 1947, the Cloud Room was a famous nightclub, attracting big-name talents such as Elvis Presley and Frank Sinatra. It closed in 2003, and the top floor of the Camlin was converted into condo suites.
The iconic famous "Makin' Whooppee" scene on the piano was choreographed. It took six hours to shoot it. Michelle Pfeiffer only had one choreography lesson, and wore knee and elbow pads during rehearsals. The red velvet evening dress that Pfeiffer wears during the sequence was designed by the film's Costume Designer Lisa Jensen.
Michelle Pfeiffer won the following Best Actress awards from the following critics' circles and associations for her performance as Susie Diamond in this film: The New York Film Critics Circle, the National Society of Film Critics, Chicago Film Critics Association Award, and the Los Angeles Film Critics Association, the latter of which she tied for the gong with Andie MacDowell for Sex, Lies, and Videotape (1989). Pfeiffer was also both nominated for the Oscar for Best Actress in a Leading Role Academy Award and the Funniest Actress in a Motion Picture (Leading Role) by the American Comedy Awards and won the Golden Globe Award for the Best Performance by an Actress in a Motion Picture - "Drama", this not being in the Golden Globes sister category of "Comedy or Musical" despite the film's comedic and musical elements.
Beau Bridges was not balding, but the script called for him to have a bald spot as Frank. In a 2014 interview, it was revealed that Jeff cut the bald spot into Beau's hair. Jeff explained, "So he let me - we had a couple of glasses of wine - and he allowed me to cut the bald patch on the back of his head." "Stupid move," Beau shot back.
Final theatrical feature film directed by Steve Kloves for four years, until Flesh and Bone (1993) which is the last cinema movie to have been directed by Kloves (as of March 2017), who predominantly has worked as a screenwriter, and has now become a producer as well.