| Cast overview, first billed only: | |||
| Robert De Niro | ... | Jack Walsh | |
| Charles Grodin | ... | Jonathan Mardukas | |
| Yaphet Kotto | ... | Alonzo Mosely | |
| John Ashton | ... | Marvin Dorfler | |
| Dennis Farina | ... | Jimmy Serrano | |
| Joe Pantoliano | ... | Eddie Moscone | |
| Richard Foronjy | ... | Tony Darvo | |
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Robert Miranda | ... | Joey |
| Jack Kehoe | ... | Jerry Geisler | |
| Wendy Phillips | ... | Gail | |
| Danielle DuClos | ... | Denise | |
| Philip Baker Hall | ... | Sidney | |
| Tom McCleister | ... | Red Wood (as Thom McCleister) | |
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Mary Gillis | ... | Bus Ticket Clerk |
| John Toles-Bey | ... | Monroe Bouchet | |
Bounty hunter Jack Walsh (Robert De Niro) is sent to find and return bail jumper and former Mafia accountant, Jonathan "The Duke" Mardukas (Charles Grodin). The FBI has had no success in locating The Duke, so when Jack finds him in next to no time, they are a little embarrassed. In order to collect his $100,000 fee, Jack must take The Duke from New York to Los Angeles. However, the Mafia and the FBI have other ideas, as does Marvin Dorfler (John Ashton), a rival bounty hunter. On their long cross-country trip to LA, the two get to know each other and they build up a strange friendship. Written by Rob Hartill
One of the smartest, funniest, and exciting buddy pictures ever made. It has never received the wonderful attention it justly deserves. The performances by the two leads (De Niro and Grodin) are wonderful and they get outstanding support from Joe Pantolino, Dennis Farina, and Yaphet Kotto. But what separates this picture from all the other action / comedies ever made is that the screenplay is so sharp and original. Easily my all time favorite movie - you know how I know that? I must have seen "Midnight Run" at least thirty times and every time I see it, it gets better and better. A true film classic and is getting rereleased on DVD in June of 2003.