The original story, a novella by Paul Theroux, was turned into a screenplay, also by Theroux (he wrote several). It was terrific. You couldn't put it down. It was a highly-atmospheric work with complex characters. We struggled to find the right director, who could give it the right kind of film noir look at which Theroux was clearly aiming. We ran into early problems when few actors we approached for the female lead were willing to play this kind of a role. The nudity was not an issue; they just didn't "identify" with Dr. Slaughter.
Signing Sigourney Weaver was a blessing but also a problem since she's taller than most leading men but fortunately, so is Michael Caine. We got lucky in that combination. We had long conferences with the director, who seemed to understand exactly what Theroux's concept was all about.
During shooting in London, the RKO team (in New York and Los Angeles; our post-production group was based in London) kept asking the head of production how things were going, how the dailies looked, etc. He told us they were on time and under budget, which was true.
When the film was finished, I went to London with the President of RKO Pictures to look at an assemble edit. It was almost unwatchable. I began to wonder if there was a good way to edit around the female lead. But it wasn't really her fault. Who could possibly undress Sigourney Weaver and make her look unsexy? That took a special kind of talent. We walked out of the screening room into the daylight of Dolphin Square and contemplated the end of our careers.
Fortunately we were able to make other pictures and have the time to spend the rest of our lives wondering exactly how to apologize for this one.