Lauren Heather McMahon's role as Taru was originally a lot bigger, but due to her having a car accident, her character was replaced by others in the script. Her scene in the film is also the only one solely directed by Richard W. Haines.
Brad Dunker became one of the lead 'Cretins' because he was one of the few people in the cast who was able to ride a motorcycle. Before that, he was a member of the crew and had a cameo as a student with sunglasses in the party scene.
When Dewey lands on the pavement in the opening scene, the first man to walk up to him is a shocked, bearded man, played by Troma co-founder and producer Michael Herz in his only on-screen performance ever.
On the DVD extra, Robert Prichard said that Heather McMahon, who played Taru, was supposed to have a bigger role. However, her car accident prevented this, and Theo Cohen, who played Muffy, stepped in and did all of the scenes written for Taru.
During the PA announcements at the start of the movie, Warren can be seen dressed in a football jersey talking to a girl, and also in his regular class right before Dewey's freak-out. The scene with Warren in the football jersey is also recycled at the end of the film as well.
Originally started as a project by Richard Haines called "Atomic High School" in which Gary Schneider would have played the teen-aged son of a family of post-apocalyptic cannibals that would trick his dates into coming over to his house "for dinner". Lloyd Kaufman eventually stepped in, the plot was changed significantly, and Schneider was given the smaller role of Pete.