Blade Runner (1982)
Joe Turkel: Dr. Eldon Tyrell
Tyrell : [Tyrell explains to Roy why he can't extend his lifespan] The facts of life... to make an alteration in the evolvement of an organic life system is fatal. A coding sequence cannot be revised once it's been established.
Batty : Why not?
Tyrell : Because by the second day of incubation, any cells that have undergone reversion mutation give rise to revertant colonies, like rats leaving a sinking ship; then the ship... sinks.
Batty : What about EMS-3 recombination?
Tyrell : We've already tried it - ethyl, methane, sulfinate as an alkylating agent and potent mutagen; it created a virus so lethal the subject was dead before it even left the table.
Batty : Then a repressor protein, that would block the operating cells.
Tyrell : Wouldn't obstruct replication; but it does give rise to an error in replication, so that the newly formed DNA strand carries with it a mutation - and you've got a virus again... but this, all of this is academic. You were made as well as we could make you.
Batty : But not to last.
Tyrell : The light that burns twice as bright burns half as long - and you have burned so very, very brightly, Roy. Look at you: you're the Prodigal Son; you're quite a prize!
Batty : I've done... questionable things.
Tyrell : Also extraordinary things; revel in your time.
Batty : Nothing the God of biomechanics wouldn't let you into heaven for.
Tyrell : "More human than human" is our motto.
Deckard : She's a replicant, isn't she?
Tyrell : I'm impressed. How many questions does it usually take to spot them?
Deckard : I don't get it, Tyrell.
Tyrell : How many questions?
Deckard : Twenty, thirty, cross-referenced.
Tyrell : It took more than a hundred for Rachael, didn't it?
Deckard : [realizing Rachael believes she's human] She doesn't know.
Tyrell : She's beginning to suspect, I think.
Deckard : Suspect? How can it not know what it is?
Tyrell : We began to recognize in them a strange obsession. After all, they are emotionally inexperienced, with only a few years in which to store up the experiences which you and I take for granted. If we gift them with a past, we create a cushion or a pillow for their emotions, and consequently, we can control them better.
Deckard : Memories! You're talking about memories!
[Batty wants Tyrell to extend his lifespan]
Tyrell : Would you... like to be upgraded?
Batty : I had in mind something a little more radical.
Tyrell : What... what seems to be the problem?
Batty : Death.
Tyrell : Death; ah, well that's a little out of my jurisdiction. You...
Batty : *I want more life, fucker/father!* (IMDb Editor's note: see trivia section for details)
Tyrell : Commerce is our goal, here. More human than human.
Tyrell : Milk and cookies kept you awake, eh, Sebastian?
Rachael : Mr. Deckard, Dr. Elden Tyrell.
Tyrell : Demonstrate it. I want to see it work.
Deckard : Where is the subject?
Tyrell : I want to see it work on a person. I want to see a negative before I provide you with a positive.
Deckard : What's that gonna prove?
Tyrell : Indulge me.
Deckard : On you?
Tyrell : Try her.