Craig introduces Dr. Peltrovich to the hospital; Chandler, Ehrlich and Morrison embark on a game of paint ball; Turner feels pressure from Auschlander when she has to do a risky operation on a litigious patient; Griffin tries to make amends with Wade and Rosenthal; Richard becomes self-conscious about his baldness.
Craig gets jealous when Peltrovich begins to steal his spotlight at the hospital; Fiscus treats a woman with leukemia who refuses treatment; Novino treats two teens who are reluctant to return to their home situations; Ehrlich has trouble getting anyone at the hospital to buy tickets to a banquet honoring him; an abused woman comes to the hospital intent on getting revenge on her husband.
Ehrlich's world is shaken by the arrival of his long lost parents; Kiem neglects her visiting husband to spend time with a patient who just lost his wife; Axelrod nearly loses a patient after deferring to Novino and Griffin on a diagnosis; Luther is reunited with Polly who wants to go off the medication that controls her Tourette's Syndrome.
Westphall finds out surprising news about Lizzie; Craig is able to track down John Doe at a book signing; prejudices surface when Chandler clashes with a veteran private practice doctor; Novino stumbles upon a black market organ trade being done in the mortuary; the board of trustees inform Auschlander of the hospital's uncertain future.
Ellen invites Griffin to stay at the Craig household; Novino is reluctant to put a blind homeless man back on the street after he no longer requires treatment; Wade has to be escorted around the hospital after losing her contact lens; Auschlander gets surprising news from an old flame.
Westphall and Auschlander must put together a plan to save the hospital; an obnoxious patient creates problems for the hospital staff; Axelrod's veterinarian father visits him at the hospital with his dog; Rosenthal's daughter returns from overseas looking unrecognizable; Turner must tell an expectant young couple that their baby may not be born healthy.
Josiah Bartlett from Boston General expresses interest in buying the hospital with an effort to recruit Craig; Morrison testifies at the parole hearing of the guy who raped him; Fiscus treats a former fraternity brother who is a dentist with fainting spells; Kiem is on edge when she cannot get a hold of her son; Ehrlich gets jealous when he sees Papandrao talking to Griffin.
Fiscus takes interest in an expectant woman who is believed to be artificially inseminated with his sperm. Three children get bored in their room and decide to wander around the hospital. Westphall is visited by a childhood friend who reminds him of an old pact. Craig and Auschlander look for ways to keep the hospital afloat.
Daniels is escorted from jail into the hospital for treatment and her homecoming does not turn out to be a happy one. Westphal reunites with an old friend. Chandler and Novino compete against one another to diagnose a patient. Rumors swirl about Ehrlich and Papandrao getting married in Mexico.
St. Eligius is reopened thanks to a new corporate owner, whose plans please Craig but leave Westphall wondering; Elliot is missing from the returnees; Fiscus finds the first patients; the Craigs' marriage seems to be headed for court.
A student nurse's lie comes back to haunt her; Warren wants better conditions for the orderlies; Craig's artificial-heart program improves as his marriage deteriorates; Wade's hostelry is filled with hostility.
Plans change for the Craig 9000; Rosenthal returns to the OR; Morrison's real life clashes with his new public image; a "bashing" incident leads to an understanding between Griffin and Brett Johnson; Ellen and Gideon start an affair.
The artificial-hear press refuses to speak to the press; Auschlander wonders about his last days on Earth; Fiscus visits his father during his suspension; sparks fly between Novino and a man called Pee Wee.