A manipulative millionaire drives a competitive wedge between a suspicious Ms. Holt and a greedy Mr. Steele with a thirty thousand dollars wager that they will not find an English writer missing in Malta within 48 hours.
A man kills the executive of a breath inhaler company. Two "singing-telegram" girls witness the killer and are suddenly targets of the murderer. It is up to Steele, Holt, and Miss Krebs to protect them and find the murderer.
The treasury of a mystery writer's guild is missing one million dollars, drawn out the guild's account by fraudulent checks. The money, donated by a recently deceased writer, was to provide the guild with a new building. Steele and Holt follow the clues uncovering two murders and aiding a senior citizen friend of the deceased writer.
A former TV actor, obsessed with the superhero that he once played (the very one whose virtues Ms. Holt used to create Remington Steele), has been accused of killing the arrogant young producer/director of an upcoming movie in which he will not be playing the hero.
Rocky Sullivan who is now a singer and her concert is sold out. She invites Steele and Laura. Her managers are not happy about her success. When an accident almost kills her, Steele and Laura try to find out what's going on. They eventually learn that her managers have oversold her and were hoping that she would flop and none of the people who own her would care. Later one of the managers is killed, Steele and Laura try to find out who killed him.
Mildred's nephew asks Steele to help him. It seems he and some prostitutes have invested in a company and the company's CEO is one of their clients. He is killed while with one of them. Now a major deal is about to come down but if his death is ever revealed it could jeopardize the deal, so they've been hiding his body. At the same time the assassin is being told by the ones who hired him that unless the public sees him dead, killing him is meaningless.
The agency has been hired by an insurance company to recover some jewels that were stolen. So Steele learns who the thief is and invites him to play poker and hopes to clean him out so that he has to get the jewels to pay Steele. But the man cleans Steele out. So while Mildred follows him, Steele has to explain to the insurance company that he lost the prop money they provided him for the poker game that he told them he would return. Mildred eventually tells them the thief is in Vegas. So Steele and Laura head there too. In the meantime, Norman Keyes the insurance ...
Steele and Laura have been hired by some men who want to run a background check on William Westfield, a man they're considering supporting for Senator. Someone takes a shot at Laura. Horton Earhart, one of their clients, wants them to declare Westfield OK but Laura after getting shot thinks it might have something to do with a brief period of time in Westfield's life that's unaccounted for, wants to continue with the investigation. Laura continues her investigation and is joined by Westfield. Steele tries to track down the shooter.