When Jesse James comes out of retirement to rob a bank, Jeff Cable is determined to arrest him. He enlists Cash to help him infiltrate the James Gang, unaware that their robberies are planned by a beautiful woman.
To recover stolen money stashed in a jail cell, Jeff masquerades as a crook and has himself arrested. A jail break interrupts his search, and it's up to Cash to save his friend from a gang of outlaws before an old flame blows Jeff's cover.
When a load of rifles is hijacked, Cable has Cash put out the word that he know an interested buyer: Jeff in disguise. The plan is complicated by the arrival of a girl from both their pasts, who, with her new husband, is seeking to buy the guns herself for a proposed revolution in Tahiti.
When the plans for a submarine are stolen, Cable is sure the thief is a powerful racketeer who is trying to shut down the Golden Gate. A disguised Jeff enters the bidding for the plans while Cash tries to steal them back.
Fishermen on the Barbary Coast are paying protection money to The Shark, though no one seems to know who he is. Cable eyes a handful of suspects, arranging a boxing match to smoke out the Shark...a match that pits the champion against Cash.