Harry reads in the paper that his old Korean War buddy died in a plane crash. His widow tells Harry about him acting strangely before his fatal flight and Harry decides to find out what really happened.
A young lady is arrested for passing counterfeit money and she calls her classmate Lester for help. Lester in turn enlists Harry's help and soon they discover that her grandfather had been printing fake money. But now he's been kidnapped.
A woman who runs a gambling club is murdered and a book of hers that's filled with incriminating photos of influential people is stolen. Harry is hired to find and destroy that book and to protect a young woman who witnessed the murder.
An ex-con gets out of prison and looks up his old girlfriend, intent on getting his hands on his old suitcase, which he says contains $300,000. Harry is hired to find the suitcase, as well as to protect the woman in the middle of it all.
Answering an old friend's plea for help, Harry arrives at the meeting and soon finds out that his friend has been killed. Harry digs into the circumstances and discovers a tangled web of smuggling, threats, and murder.
The fourth "Lester" episode is a pilot for what would have been a spin off "Fong and Hodges" series. (Sadly, the episode's relatively low ratings may have been the tipping point in ABC deciding to cancel "Harry O." Harry receives a note from Simon Applequist, asking Harry to come to a meeting at Applequist's palatial mansion. Applequist is a fabulously successful businessman who made more enemies than even he could count. Applequist greats Harry and introduces him to his various relatives -- one of whom is Lester Hodges. Then he fixes a baleful glare on the group and ...
A young widow has a malpractice suit against the doctor who was treating her deceased husband, but after she is threatened by two men to drop the suit, her mother hires Harry to look into the Dr.'s past. Dead bodies begin piling up around Orwell, including Spence, his auto mechanic. The investigation leads Harry into the world of organized crime, hit-men and the safe-deposit box of the deceased husband.