Dr. Sean Jamison gets a phone call from Claire Wells who has an unusual request. She wants him to diagnosis her son Scott with an illness that will keep the boy from going on a sailing trip with his father.
Dr. Sean is looking forward to his birthday and the celebration his daughter Anne, plus Ronnie and Puni have planned. The arrival of his most irritating patient changes things as he gets stuck in an abandoned mine.
Nurse Puni and her friends decide to protest a company's environmental policy it gets Puni arrested. Sean's intervention also put him behind bars but wben he meet the lady in charge of the corporation love blossoms.
Dr. Sean decides it is time to quit smoking and enlists the help of his daughter Anne plus staff. The experience isn't easy, turning the pediatrician at moments cranky but also creating comical moments.
Anne is tired of her father's "helpfulness" in her cases and comes up with a solution. They divide the patients alphabetically but Sean can't seem to remember his abcs and continues to interfere in Anne's medical decisions.
A tough as nails army officer, Marshall Clark, shows up for a medical diagnosis despite Dr. Sean being a children's physician. After an examination Sean finds nothing wrong despite the man's insistence of an illness.
Ten year old Kenny Phelps imagines himself an international spy and his antics wreak havoc. Kenny disappears from Dr. Sean's, office leading the pediatrician and staff on an exhaustive search for the boy.