Winston Ainslee, an aging and well educated gunfighter, employs Paladin to help him, gracefully and with honor, end his career. But the last person he killed has a brother seeking revenge; and he just arrived in town on the stage with Paladin.
Don Luis has hired Paladin to escort his daughter away from her home and a peasant boy who has grown up and has eyes for her. The boy has thoughts of revenge for the mistreatment at her father's hand and tries to do exactly that; unless Paladin can intervene.
Paladin is hired by first class chef Etienne (Werner Klemperer) to transport a large piece of plate glass from San Francisco into mining country for his restaurant window. Promised a first-class meal and $1000 for accomplishing this task successfully, Paladin agrees. Along the way there are various difficulties which include Indians, an envious rancher and a drunk who loves the sound of breaking glass.
A disgraced General summons Paladin to his deathbed to deliver a message to a personal enemy. Gen. Crommer tried to court-martial Paladin in the Civil War, so Paladin's a very reluctant messenger. Paladin returned the favor then and takes the assignment now, while back at the wealthy Crommer's mansion, his heirs celebrate the miser's impending demise.
Webster, a man with three daughters, thinks he's found gold. He's worried that feisty Doris, a woman with three sons, is going to take it away from him so he hires Paladin to protect his interests. Paladin does some research before leaving San Francisco and discovers a solution which breaks the impasse in more ways than one.
Paladin receives a bank draft for $1000 asking him to "come kill a tiger before it kills me." In his host's mind this tiger curse is warranted as he wounded a tiger while in India and it came back to a village only to slaughter 100 of its residents. Paladin then learns of a circus coming to town. Its main attraction - a tiger!
Summoned to a beleaguered Western village to drive off a desperado, Paladin meets a young Native American, who's taken a correspondence course in being a Marshal, and plans to install himself as lawman for the tiny town. Paladin is charmed by the sincerity and honesty of the seemingly naive Charley Red Dog, whose grandfather was shot for sport in the hamlet. Paladin figures they can work together, though Charley doesn't want any help, plus the town puts on an all-out blitz at high noon, to avoid a Red Dog for Marshal...
Ben Harvey hires Paladin to escort him to a town called Gila where he has a family store. Now that he is out of prison, he wants to get on with his life despite his past. The only thing stopping him is a town bent on hanging the rest of the Harvey clan.
A U.S. general is teaching Apaches European military tactics, so Paladin is hired by military intelligence to capture or kill the deserter. The general's Apache wife was raped by his own troops, so now General Nunez's combined forces with her tribe near Alamogordo to start a war against the U.S. Cavalry. Paladin served with the General in the Union Army, and is skeptical about the fierce, All Army ex-Indian fighter.
C. Palmer sends for Paladin to clean up Cedar Wells - a place where folks lose at faro, lose their lives and the cattle she tries to sell there. With the help of Laredo Perkins, Paladin hatches an idea of how exactly he can earn his fee.
Ike Brennan's wife Maureen is being held hostage by Indians. He hires Paladin to escort him to where the Indians will exchange Maureen for food and blankets. Before Paladin can get Maureen back, he must contend with a nosy cavalry patrol and a dangerous secret which just might get everyone killed.
Paladin intercedes to delay a stalker until his prey Jenny has left San Francisco, but another man, who's eerily calm, KOs Paladin from behind. On horseback, Paladin catches up with her stagecoach, and forces the stalker off, but the silent partner quietly remains on-board, undetected. While all the men on the trip clear a landslide blocking the stagecoach's path, someone else entirely kidnaps Jenny! Again, Paladin saddles up to go after Jenny.
An Indian chief asks Paladin for help. His son has been convicted of murder by the army and sentenced to be executed. The chief wants Paladin to help make sure that the boy will be buried according to tribal customs, which he doesn't believe the army will do. Paladin agrees and travels to the fort where the son is being held. However, the more he finds out about the case, the more he becomes convinced that the young man was actually framed for the murder for which he's to be executed.
Paladin rides upon a group of men heading to Mercerville. When they see a stranger on the cliff side swept away by an avalanche, it's soon revealed why each of them has their reasons why they can't or won't see if he is still alive even though one is a doctor.
Paladin is accused by Bonanza's citizenry of swiping the treasured painting behind the bar of the hamlet's last remaining saloon. The portrait of a vibrant and gorgeous former woman resident, sustains the spirits of elderly townsmen, remembering her and the area's halcyon Gold Rush days.
A wealthy financier, Commodore Guilder, hires Paladin to protect him from Quanah Parker, a half-Indian, half-white warrior. Arriving at Adobe Wells, Paladin discovers that Guilder did not tell him the full story.
Vain old gasbag challenges a young fop to a duel, so Paladin is hired to go to New Orleans to stop it. Complicating Paladin's assignment are his attraction to the older combatant's luscious daughter, and that the younger man imports feared Texas gunslinger Sledge as his second.
Paladin drops his current seduction, to instead kill a husband and marry the rich widow. That's his cover for the assignment from husband Haskel, who reads a chilling message between the lines in his drop-dead wife's personals ad: she's had it with being a trophy. She wants Haskel's head over the mantle now. When Paladin arrives at the couple's ranch, there's a long line of willing applicants already.
A man is shot at by a woman because he killed her little brother during the Civil War. He has been running from her since then. Paladin offers to contact the police but when that is refused, he offers his card and services.
When Doggie's shooting arm is injured winning a gunfight, the impoverished citizens dig deep to rabidly bet on who will finish off their local menace (and when). Passerby Paladin wants nothing to do with it, but decides even the despicable gunslinger deserves some justice, so he agrees to get him out of town so he can stand trial.
Several travelers are held by gunpoint at a ferry crossing, including Paladin and his prisoner. What fate awaits them soon appears in the form of a blind father seeking vengeance for his son's killer which he believes to be one of them.
Paladin is hired to bring back from Mexico an heir to a sizable fortune. One catch -- the heir may have to spend several years in jail for crimes he committed. But is it jail Paladin is leading him to or something else?
Billy Banjo Jones is running for state senate, supported by his rich and domineering wife, Elise. But he hires Paladin to give protection to his opponent, Jansen, because he fears that Elise may do murder to ensure his successful election.
Morgan Gibbs hires Paladin to bring his son in alive for the murder of his fiancee. He tries to but a bounty hunter is there first and shoots him in the back. Now Morgan wants Paladin to have a kangaroo style trial for his son's murder.
Lane Kilmer brings Paladin to the bedside of his dying mother, who wishes to hire Paladin to find her son Martin, lost for 20 years. Paladin decides to follow the lead of Mr. Edwards, another person engaged by Mrs. Kilmer to find Martin.