The Invisible Man (1933)
- The novel takes place in the 1890s, the film takes place in 1933.
- In the novel, the invisibility process includes a chemical compound that take the color out of organic material, along with the use of "vibrations" similar to X-rays. In the film, drugs alone do the trick.
- In the novel, Griffin remains almost a completely mysterious person, with no fiancée or friends. In the film, he is engaged to a woman and has the support of her father and his associate.
- In the novel, Griffin is an egomaniac with no empathy for his fellow man, but he had these traits before making himself invisible. In the film, the invisibility drug causes him to go mad.
- In the novel, Kemp lives. In the film, Griffin kills him.