This was Boris Karloff's first credited starring role. His name had been left off the Frankenstein (1931) publicity packages and only credited in the end credits of that film.
Although this was the only film with both Raymond Massey and Boris Karloff, Massey would go on to play Karloff's role in the film Arsenic and Old Lace (1944) because the producers of the Broadway show, which was still running when the film was shot, wouldn't release Karloff.
A movie poster for this film sold at Christie's in New York in December 1991 for $48,400, making it at the time the most valuable poster ever sold.
Was withdrawn from circulation when the remake, also titled The Old Dark House (1963) by William Castle Productions, was released. This film was considered to be lost until director Curtis Harrington discovered a printable negative.