Mystery, US Prime Video ($0.00 with Membership), Exclude Titles I've Seen (Sorted by Popularity Ascending)
2. The Expanse (2015– )
TV-14 | 60 min | Drama, Mystery, Sci-Fi
A police detective in the asteroid belt, the first officer of an interplanetary ice freighter and an earth-bound United Nations executive slowly discover a vast conspiracy that threatens the Earth's rebellious colony on the asteroid belt.
4. Hereditary (2018)
R | 127 min | Drama, Horror, Mystery
After the family matriarch passes away, a grieving family is haunted by tragic and disturbing occurrences, and begin to unravel dark secrets.
Votes: 137,954 | Gross: $44.07M
6. Bones (2005–2017)
TV-14 | 40 min | Comedy, Crime, Drama
Forensic anthropologist Dr. Temperance "Bones" Brennan and cocky F.B.I. Special Agent Seeley Booth build a team to investigate murders. Quite often, there isn't more to examine than rotten flesh or mere bones.
7. House M.D. (2004–2012)
TV-14 | 44 min | Drama, Mystery
An antisocial maverick doctor who specializes in diagnostic medicine does whatever it takes to solve puzzling cases that come his way using his crack team of doctors and his wits.
8. Star Trek: The Next Generation (1987–1994)
TV-PG | 44 min | Action, Adventure, Mystery
Set almost 100 years after Captain Kirk's five-year mission, a new generation of Starfleet officers set off in the U.S.S. Enterprise-D on their own mission to go where no one has gone before.
9. Endeavour (2012– )
TV-14 | 89 min | Crime, Drama, Mystery
Set in the 1960s, the show follows Endeavour Morse in his early years as a police constable. Working alongside his senior partner DI Fred Thursday, Morse engages in a number of investigations around Oxford.
10. Annihilation (2018)
R | 115 min | Adventure, Drama, Horror
A biologist signs up for a dangerous, secret expedition into a mysterious zone where the laws of nature don't apply.
Votes: 217,395 | Gross: $32.73M
11. The X-Files (1993– )
TV-14 | 45 min | Drama, Mystery, Sci-Fi
Two F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
13. True Blood (2008–2014)
TV-MA | 55 min | Drama, Fantasy, Mystery
Telepathic waitress Sookie Stackhouse encounters a strange new supernatural world when she meets the mysterious Bill, a southern Louisiana gentleman and vampire.
14. Papillon (I) (2017)
R | 133 min | Crime, Drama, Mystery
Wrongfully convicted for murder, Henri Charriere forms an unlikely relationship with fellow inmate and quirky convicted counterfeiter Louis Dega, in an attempt to escape from the notorious penal colony on Devil's Island.
Votes: 28,779 | Gross: $2.34M
15. The Good Wife (2009–2016)
TV-14 | 43 min | Crime, Drama, Mystery
Alicia has been a good wife to her husband, a former state's attorney. After a very humiliating sex and corruption scandal, he is behind bars. She must now provide for her family and returns to work as a litigator in a law firm.
16. Psych (2006–2014)
TV-PG | 44 min | Comedy, Crime, Mystery
A novice sleuth is hired by the police after he cons them into thinking he has psychic powers which help solve crimes. With the assistance of his reluctant best friend, the duo take on a series of complicated cases.
18. Hannibal (2013–2015)
TV-14 | 44 min | Crime, Drama, Horror
Explores the early relationship between the renowned psychiatrist and his patient, a young FBI criminal profiler, who is haunted by his ability to empathize with serial killers.
20. Zodiac (2007)
R | 157 min | Crime, Drama, Mystery
In the late 1960s/early 1970s, a San Francisco cartoonist becomes an amateur detective obsessed with tracking down the Zodiac Killer, an unidentified individual who terrorizes Northern California with a killing spree.
Votes: 384,795 | Gross: $33.08M
22. Mother! (2017)
R | 121 min | Drama, Horror, Mystery
A couple's relationship is tested when uninvited guests arrive at their home, disrupting their tranquil existence.
Votes: 150,931 | Gross: $17.80M
23. Arrival (II) (2016)
PG-13 | 116 min | Drama, Mystery, Sci-Fi
A linguist is recruited by the military to communicate with alien lifeforms after twelve mysterious spacecrafts land around the world.
Votes: 502,158 | Gross: $100.55M
26. Shutter Island (2010)
R | 138 min | Mystery, Thriller
In 1954, a U.S. Marshal investigates the disappearance of a murderer, who escaped from a hospital for the criminally insane.
Votes: 989,679 | Gross: $128.01M
27. You Were Never Really Here (2017)
R | 89 min | Crime, Drama, Mystery
A traumatized veteran, unafraid of violence, tracks down missing girls for a living. When a job spins out of control, Joe's nightmares overtake him as a conspiracy is uncovered leading to what may be his death trip or his awakening.
Votes: 66,671 | Gross: $2.52M
28. The Killing of a Sacred Deer (2017)
R | 121 min | Drama, Mystery, Thriller
Steven, a charismatic surgeon, is forced to make an unthinkable sacrifice after his life starts to fall apart, when the behavior of a teenage boy he has taken under his wing turns sinister.
Votes: 85,999 | Gross: $2.29M
29. The Killing (2011–2014)
TV-14 | 45 min | Crime, Drama, Mystery
A police investigation, the saga of a grieving family, and a Seattle mayoral campaign all interlock after the body of 17-year-old Rosie Larsen is found in the trunk of a submerged car.
34. First Reformed (2017)
R | 113 min | Drama, Mystery, Thriller
A minister of a small congregation in upstate New York grapples with mounting despair brought on by tragedy, worldly concerns and a tormented past.
Votes: 30,236 | Gross: $3.45M
36. The Closer (2005–2012)
TV-14 | 46 min | Crime, Drama, Mystery
Deputy Police Chief Brenda Johnson runs the Priority Homicide Division of the LAPD with an unorthodox style. Her innate ability to read people and obtain confessions helps her and her team solve the city's toughest, most sensitive cases.
38. The ABC Murders (2018– )
TV-14 | Crime, Drama, Mystery
In 1933, retired detective Hercule Poirot is targeted by a taunting killer who sends letters signed "ABC", which Poirot must decode in order to discover the identity of the murderer.
40. In Plain Sight (2008–2012)
60 min | Crime, Drama, Mystery
U.S. Marshall Mary Shannon must hunt down witnesses for federal cases in the witness protection program while also managing rather dysfunctional family and her own personal life.
41. The Missing (2014– )
TV-14 | 60 min | Crime, Drama, Mystery
When Tony and Emily Hughes travel to France with their 5-year-old son Oliver, their family holiday turns into a nightmare when Oliver disappears from a large celebrating crowd in Northern France.
42. Absentia (2017– )
TV-MA | 60 min | Crime, Drama, Mystery
After being declared dead in absentia, an FBI agent must reclaim her family, identity and innocence when she finds herself the prime suspect in a string of murders.
43. Unsane (2018)
R | 98 min | Drama, Horror, Mystery
A young woman is involuntarily committed to a mental institution, where she is confronted by her greatest fear--but is it real or a product of her delusion?
Votes: 29,898 | Gross: $7.73M
44. Sherlock Gnomes (2018)
PG | 86 min | Animation, Adventure, Comedy
Garden gnomes, Gnomeo & Juliet, recruit renowned detective Sherlock Gnomes to investigate the mysterious disappearance of other garden ornaments.
Votes: 7,479 | Gross: $43.24M
47. Hugo (2011)
PG | 126 min | Adventure, Drama, Family
In Paris in 1931, an orphan named Hugo Cabret, who lives in the walls of a train station, is wrapped up in a mystery involving his late father and an automaton.
Votes: 282,600 | Gross: $73.86M
49. Escape Plan 2: Hades (2018)
R | 96 min | Action, Crime, Mystery
Years after he fought his way out of an inescapable prison, Ray Breslin has organized a new top-notch security force. But when one of his team members goes missing, Breslin must return to the hell he once escaped from.