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With the Apocalypse looming, Sam and Dean realize they are out of options and make heart-breaking decisions that will change their lives forever.

Dean and Sam are thrown into an alternate universe by the Trickster where they are characters in different TV series.

To protect Sam and Dean from a surprise attack from Raphael, Balthazar sends them both into an alternate universe where their lives are a TV show called Supernatural (2005).

Sam, Dean, and Castiel are transported into the animated world of Scooby Doo where they join forces with the Scooby gang to solve a ghostly mystery.

Sam relives the same day over and over, continually having to deal with Dean's death.

Dean hits an emotional rock bottom after a devastating personal loss. The Yellow Eyed Demon begins a calculated strategic move to unleash the armies of hell.

Sam tries to move on without his brother and becomes hardened and more reckless in the way he hunts. Bobby and his psychic friend Pamela try to contact the other side to find out more about Dean's ultimate fate.

Sam and Dean investigate a haunting at a theatre.

Sam and Dean's road trip to fight monsters and demons is chronicled entirely from the Impala's perspective.

Amara unleashes a dark fog on a small town that causes everyone to go mad. Dean and Sam realize this is a stronger version of the original black vein virus Amara previously unleashed.

Dean is attacked by a Djinn and finds himself in a new reality where his mother is still alive but another dead woman keeps appearing to him.

Sam and Dean are arrested by Agent Henriksen and thrown into a jail cell in Colorado just as an army of demons makes their first move under a new leader who wants Sam dead.

Sam and Ruby try to kill Lilith. Zachariah and Castiel tell Dean he must play his part in stopping Lucifer.

Sam and Dean capture Crowley to finish the trials and close the gates of Hell. Castiel and Metatron continue the trials to close the gates of Heaven. Sam is left with a huge decision.

Sam and Dean look to occult lore for a solution to their latest problem, but instead of a resolution, they find much more than either of them had anticipated.

Sam and Dean seek help from Bobby Singer, an old family friend in their mission to save their father from Meg. The brothers set a trap for Meg.

In the aftermath of the car crash, the surviving Winchesters go to the hospital, where one is stalked by a Reaper while another must consider sacrificing himself to save the others.

The Winchesters are called regarding a robbery of their father's storage unit, and track down the robbers to find the item stolen is a cursed rabbit's foot, which provides great luck until lost, and once lost the previous owner dies within a week. Sam picks up the foot and has great fortune, until it is pickpocketted away by the mercenary Bela. Dean must then get it back before Sam's bad luck gets him killed. To complicate the whole situation, Gordon, from his prison home, has convinced two other hunters that Sam is pure evil and must be killed.

Dean's time is up and he has to pay the Devil his due. When Lilith resurfaces in New Harmony, Indiana terrorizing a family to no end Sam, Dean, and Bobby steal Ruby's knife and confront the mother of all demons in a battle to the death.

Dean and Sam discover a comic book series that accurately details their lives.

Castiel sends Dean back in time to 1973 where he encounters younger versions of his parents and for the first time meets his grandfather Samuel Campbell who holds a secret that sheds a light on the Winchester Family's connection to the hunter community.

Dean and Sam get to know the whereabouts of Lucifer and want to hunt him down. But Lucifer is well prepared and is working his own plans.

Bobby sells Crowley his soul in exchange for the location of Death, while Pestilence infects the Winchesters with a deadly disease.

Bobby is close to dying. He must confront his worst memory to escape, before his reaper catches up to him.

The influence of the mark on Dean reaches new heights, as Metatron begins to reveal himself to humanity.