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Carter and Lucy are discovered and the staff struggles to save them and go on with normal patient care.

Dr. Greene's final days are spent in Hawaii with Rachel, teaching her to drive and surf. When he suffers a seizure, Elizabeth is called. Mark refuses to go home. He manages to make amends with his daughter before his eventual death.

Dr. Benton has to deal with the aftermath of his mother's fall and crosses the line with the surgical attending when he insists on scrubbing in for her operation. Dr. Greene deals with Jodi O'Brien who is two weeks away from giving birth. With the obstetrics attending unavailable, he decides to try to deliver her baby in the ER, with tragic results.

As Carter prepares to open a new facility for the underprivileged, some old friends/colleagues gather. Rachel Greene, Mark Greene's daughter, applies for an internship at County.

Dr. Greene and Dr. Corday bond with their parents, Lucy cares for a patient with a psychotic break, and Valentine's Day celebrations in the ER end tragically.

Doug saves a kid who's stuck in a flooded culvert and becomes a local hero when a TV helicopter films part of the rescue operation.

Because of benzene that's been spread, the ER has to close. Weaver gets felled and Carter has to take the lead.

As Dr. Greene's brain tumor begins affecting his coordination, he becomes concerned that his fate will be similar to the terminally ill patients he treats.

Dr. Carter reads a letter from terminally ill Dr. Green to the ER staff. Dr. Weaver lashes out at a mentally challenged patient. A terminal, homeless man continues asking for Dr. Green.

A girl drops off a sick baby at the ER and then leaves; Carter may get a kidney transplant; Gates and Daria care for an elderly woman with multiple sclerosis; Neela and Sam are in Seattle to transport a heart for Joanie Moore, while Doug and Carol are concerned that the donor's grandmother might not consent.

An ex con and alcoholic patient, Charlie Metcalf (Ray Liotta) passes out in the waiting room and is brought to the emergency room by the doctors. It shows the real time of 45 minutes with an patient of his life story and his final days in the ER, which touches the doctors treating him.

Chaos reigns in the ER when two prisoners are brought in for treatment, but instead plot a violent escape. Their desperate actions place one doctor in harm's way, and forces one nurse to become a tool in their plan.

Trying to rescue a three-year-old girl from drowning in a nearby lake, Banfield is reminded of her own experience at County with Dr. Greene caring for her son.

The ER staff's slow snow day becomes chaotically hectic when the casualties of a 40 car traffic accident flood in.

As the result of a school shooting, Kovac and Benton care for the gunman and his victims. Abby discovers that Carter has been illegally injecting pain relievers. Greene and Weaver confront Carter about his problem, and Weaver orders him to enter a drug rehabilitation center or leave the hospital permanently.

The ER is flooded with foster care home residents, attacked by a shooter bent on tracking down his son, who, with the help of Dr. Greene, was put into the foster care system amid allegations he was being abused by his father.

After some staff members are caught going through a dominatrix's bag, Weaver makes them attend a sexual harassment seminar, where they learn about each other.

Casualties of a disaster flood the ER, which is short-handed because everyone is at Dr. Carter's going-away party because he's leaving the ER after 11 years. Dr. Pratt looks for the courage to confront his father, Charlie.

The pilot for the popular TV series is set during 24 frantic hours in the lives of a group of doctors, nurses, and staff members of a busy emergency room at a Chicago hospital. They deal with the seemingly endless casualties that stumble into their place of employment. The central characters are the chief resident and family man Dr. Mark Greene, who is considering a job in private practice due to pressure from his demanding law student wife Jennifer; outgoing Dr. Doug Ross, who deals with cases in his own personal way; straight-arrow Dr. Susan Lewis, trying to get by another long 36-hour shift; inexperienced third-year med student John Carter; cocky surgical resident Dr. Peter Benton; and troubled chief nurse Carol Hathaway.

Mark has to work for the fourth night in a row while a lot of the staff are absent and the number of patients is towering.

On Thanksgiving Day, a helicopter crash outside the ER leaves several injured. Alex tries to bring Sam and Luka together.

On Thanksgiving Day Carol goes into labor. She's able to get to the ER only thanks to Luka's help. She delivers the first baby in the ER, but the second causes some trouble. Greene leaves Elizabeth to deal with his father and daughter, as he rushes to assist Carol.

Just when the ER is understaffed and swamped, two children who were brought in turn out to have full blown smallpox. The entire ER must be locked down. The staff needs to improvise while they battle not only the disease but also frayed tempers.

Greene prepares to bury his father. Chen worries about Carter's mood swings. After witnessing the interaction between a dying woman and her family, Hathaway realizes she wants her family together and flies to Seattle to join Ross.

Shep and Raul go in a burning house without the proper equipment to save three children.