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In the Series Finale, Mama is trying to calm Naomi down, who freaks out when Vint leaves her to go to work. Mama tells her the story of how great Carl was when their first child was born. Of course she's lying just to make Naomi feel better. She then tells Iola the real story. Seems she had to take the bus to the hospital when Carl refused to come out of the bathroom, as she went into to labor. Bubba, who's trying to make the college Water Polo team, is driving Mama nuts by running up and down the stairs. When Naomi finally goes into labor, after seemingly being pregnant forever, she refuses to go to the hospital until she gets her hot rollers. Vint, who gets home just then, goes to get the car and panics and smashes his pickup into Mama's car, then promptly passes out when Mama tells him to calm down. Bubba (who made the Water Polo team) and Iola show up a little later and hear a baby cry coming from the trailer. As it turns out, Mama had to deliver the baby, and now they need to pick a name for the Harper's newest addition, a beautiful girl. Vint suggests they call it Thelma, but Naomi wants to name it Tiffany. They compromise and name it Tiffany Thelma.

Naomi and Vint read in a magazine how it will cost $168,000 dollars to raise their kid. So they set about coming up with a scheme to make some fast money. Just then Bubba comes home feeling bad, and Mama gives him some of her "Mother Harper's Tonic" and that gives Vint and Naomi an idea. They could sell the tonic and make a fortune. So Naomi gets some bottles from the recycling bin at Food Circus and they start to bottle it. It sells fast and everyone wants more. So Bubba takes it to his swim meet and Thelma takes it with her to the Church Ladies League meeting. Everyone samples some and it's a huge hit as everyone including Thelma and Iola get up and start dancing. Alberta even tells Thelma that she's gonna nominate her for CCL Woman of the Year. Bubba comes home and tells Vint and Naomi about what happened at the swim meet, his team lost every race and they sent the tonic to be analyzed and it came back that it was 35 percent alcohol, which closes down the family's business.

Mama's home gets new residents when her grown son Vint moves in with his two children.