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Five years after Lisa went missing on the hiking trail GR5, her friends Zoë, Michiel, and Ylena decide to make the same journey to commemorate her. They are unexpectedly joined by Piet, her father.

The group sets out with Piet trailing behind. It becomes clear that they all have different reasons for making the journey. Asim, Lisa's ex-boyfriend and former jihadi, wants to join the hike.

Asim's arrival divides the group. They learn that during her stay in the Ardennes, Lisa found out that her father had an affair. Asim confesses that he is on the run. In Luxembourg, the group discovers a new trace of Lisa.

The journey continues through the desolate region of la Lorraine. Bart, Ylena's husband, visits the group with his camper. Piet discovers that Lisa and Bart have seen each other during her journey. Asim's past finally catches up with him.

The traumatic events seem to have put an end to the commemoration. Piet meets inspector Pol Martin where he last spoke to his daughter. Asim turns out to be the driver of the red van that Lisa got into just before her disappearance.

Lisa's cell phone case turns up near a burned-out hut. There, investigators discover Lisa's fingerprints dating from two years after her disappearance. Inspector Pol Martin seems to know more than he is willing to share.

The group is in Geneva, where Lisa's backpack was recovered. Zoë receives an anonymous note from someone claiming to know Lisa. In the Alps, disaster strikes when Piet loses his balance and Asim plunges to death trying to save him.

After the devastating events in the Alps, the group falls apart and Zoë continues the GR5 hike on her own. Upon her arrival in Nice, she finally discovers what really happened to Lisa.

Sylvia is a wealthy woman whose marriage falls apart when her husband is arrested. Without financial resources, she moves with her children to the brothel that she inherited from her deceased father.

After the discovery of human remains on the Chaussée d'Amour the federal detective Ludo Beets starts an investigation. He has his suspicions. In the meantime Sylvia meets the local pharmacist and her son Sep makes a grave mistake.

Sylvia starts a new job, Sep and Eva pay their grandmother a visit and Ludo goes to the hospital to confront Willy. Sep's mistake comes with expensive consequences and the Cats girls ask Sylvia to exploit their brothel.

Sylvia has decided to exploit Cats. She starts renovating the place, she starts looking for new girls and she plans a big opening party. The Cats ladies bump into some obstacles: Bijou gets trapped and Sandy has a problem with a customer.

Ludo and Sam discover new clues about the twenty year old murder case. Sylvia and Jérôme are starting to fall in love with each other and decide to have a dinner. Meanwhile Willy makes a deal with an Albanian pimp.

Colette is interrogated by Ludo and Sam. When she returns to Cats she notices that Bijou is flirting with her clients. Sylvia isn't happy when Bijou decides to work for Alek. Eva struggles with heartbreak and Ludo is getting more answers.

Ludo figures out what Valentina's statement to the police from 20 years ago is really about and her "horse with a clown's face". Sandy discovers she has a problem. Joëlle ends up in the difficult situation.

Sylvia bans Willy from Cats. The police arrest Collette over Allaire's murder. Joëlle is slowly recovering from her attack, whilst Bijou and Sandy plan revenge.

The marriage of Sylvia and Daniël can no longer be saved. Therefore Daniël seeks solace in the arms of Sandy. Sylvia and Collette come to heads. Willy takes drastic measures.

Willy's death causes a shockwave along the Chaussée. Whilst everyone's mourning, Ludo is convinced that he doesn't yet know the truth about the murder.

At her funeral, Kato finds more people who are able to see her and manages to point the police team in the right direction: Hotel Beau Séjour.

Acting on a tip from local psychic, Jef, the Federal police team search the hotel room where Kato was murdered and find blood in the bathroom, so the investigation can progress. Meanwhile, Kato's friend Inès may be up to something.

Grand Opening of the hotel. Schneider goes too far abroad. Charlie confronts Kato with her surprising behaviour the night she died. A Confession! A link between those who see Kato?

Alexander gets caught doing something, and threatens Kato, but she turns it around to try to get something from him. The drug dealer is pursued, creating problems and surprises. Drama is emitted by Luc, Sofia and Cyril.