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- The quirky spin on Conan Doyle's iconic sleuth pitches him as a "high-functioning sociopath" in modern-day London. Assisting him in his investigations: Afghanistan War vet John Watson, who's introduced to Holmes by a mutual acquaintance.
- Sherlock Holmes faces a sinister case risking friends' lives. American Amelia joins, seeking her father after her mother's murder. Despite differences, they solve a conspiracy and her mother's case.
- Detective Sherlock Holmes and his stalwart partner Watson engage in a battle of wits and brawn with a nemesis whose plot is a threat to all of England.
- The plot is unknown at this time.
- Detective Sherlock Holmes is on the trail of criminal mastermind Professor Moriarty, who is carrying out a string of random crimes across Europe.
- Sherlock Holmes and Dr Watson solve the mysteries of copper beeches, a Greek interpreter, the Norwood builder, a resident patient, the red-headed league, and one final problem.
- TV SeriesA 19-year-old Sherlock Holmes, finds himself entangled in a murder at Oxford that jeopardizes his freedom. His first case, tackled recklessly, leads him to uncover a far-reaching conspiracy that alters his path forever.
- A film projectionist longs to be a detective, and puts his meagre skills to work when he is framed by a rival for stealing his girlfriend's father's pocketwatch.
- When assorted people start having inexplicable delusions that lead to their deaths, a teenage Sherlock Holmes decides to investigate.
- Sherlock Holmes and Dr Watson solve the mysteries of the devil's foot, Silver Blaze, Wisteria Lodge and the Bruce-Partington Plans.
- Garden gnomes, Gnomeo and Juliet recruit renowned detective Sherlock Gnomes to investigate the mysterious disappearance of other garden ornaments.
- Holmes and Dr. Watson solve the mysteries of the Disappearance of Lady Frances Carfax, Thor Bridge, Shoscombe Old Place, The Boscombe Valley Mystery, The Illustrious Client and The Creeping Man.
- When a bored Holmes eagerly takes the case of Gabrielle Valladon after an attempt on her life, the search for her missing husband leads to Loch Ness and the legendary monster.
- A horrifyingly fresh look at the iconic detective that delves into his worst nightmares that haunt him about one case he could never solve.
- The master sleuth hunts his archenemy, Professor Moriarty, who is planning the crime of the century.
- When Jazz Ramsey and her crime detection dog Zeus stumble upon an old crime scene, the K9 trainer, her star pup, and ex-boyfriend and lead detective Nick are thrown into the investigation.
- The last installment of Sherlock Holmes' investigations.
- Early in his crime-solving career, Sherlock Holmes attempts to prevent Moriarty from cornering the heroin market.
- During WWII, several murders occur at a convalescent home where Dr. Watson has volunteered his services. He summons Holmes for help and the master detective proceeds to solve the crime from a long list of suspects including the owners of the home, the staff, and the patients recovering there.
- Sherlock Holmes and Watson do battle with their nemesis, Professor Moriarity, over an ancient necklace attributed to Cleopatra.
- Sherlock Holmes and Doctor Watson must protect a Swiss inventor of an advanced bomb sight from falling into German hands.
- When a German saboteur jeeringly predicts to the nation new depredations, via their radio "Voice of Terror", the Intelligence Inner Council summons Sherlock Holmes (Basil Rathbone) to help in the crisis.
- The adventures of master detective Sherlock Holmes as he and his assistant, Dr. Watson--and, somewhat reluctantly, the bumbling Inspector Lestrade--battle criminals in London.
- A serial killer stalking the teen-aged daughters of the aristocracy brings Sherlock Holmes out of his drug-filled semi-retirement.
- The younger brother of the consulting detective tries to steal Sherlock's glory by solving an important case assisted by an eccentric Scotland Yard detective and a lovely but suspicious actress.