Seth MacFarlane in Family Guy (1999)
Stewie (from Family Guy) in Silence of the Lambs: After Clarice exits another investigative quid-pro-quo exchange with Lecter, a sociopath baby enters, stage right, and tries to learn from Hannibal, as well. Of course, unlike Starling's, Stewie's motives are of a more, shall we say, nefarious nature. (suggested by rubyfruit)