According to Showtime's co-president of entertainment, Gary Levine, the 10th season cast is set to return. There's hope that Emmy Rossum will return before the end.
Here's the renewal announcement from Showtime:
Showtime Announces 11th And Final Season Of Shameless To Premiere This Summer
Los Angeles – January 13, 2020 – Showtime has announced that it has picked up an 11th and final season of its hit comedy series Shameless, premiering this summer. Shameless, which originally premiered in the winter of 2011, ranks as the network’s no. 1 comedy, its longest-running series and has the youngest-skewing audience of any Showtime series. Season