George Clooney and Elisabetta Canalis at an event for The 82nd Annual Academy Awards (2010)

George Clooney at an event for The 82nd Annual Academy Awards (2010)

George Clooney, Morgan Freeman, Jeff Bridges, and Jeremy Renner

George Clooney, Colin Firth, Morgan Freeman, Jeff Bridges, and Jeremy Renner

James Cameron, George Clooney, Meryl Streep, and Lee Daniels

George Clooney, Vera Farmiga, and Renn Hawkey

Brad Pitt and George Clooney in Wolfs (2024)

Brad Pitt, George Clooney, and Austin Abrams in Wolfs (2024)

George Clooney and Al Pacino in Ocean's Thirteen (2007)

Brad Pitt and George Clooney in Ocean's Eleven (2001)

George Clooney and Scott Jacoby in Return to Horror High (1987)

George Clooney in Return to Horror High (1987)

George Clooney and Lori Lethin in Return to Horror High (1987)

George Clooney and Michelle Pfeiffer in One Fine Day (1996)

George Clooney, Michelle Pfeiffer, Alex D. Linz, and Mae Whitman in One Fine Day (1996)

George Clooney and Quentin Tarantino in From Dusk Till Dawn (1996)

Brad Pitt, George Clooney, Matt Damon, Andy Garcia, Casey Affleck, Elliott Gould, Scott Caan, Bernie Mac, Carl Reiner, Eddie Jemison, and Shaobo Qin in Ocean's Eleven (2001)

George Clooney, Arnold Schwarzenegger, Alicia Silverstone, Uma Thurman, and Chris O'Donnell in Batman & Robin (1997)

Brad Pitt, George Clooney, Julia Roberts, Don Cheadle, Matt Damon, Andy Garcia, Catherine Zeta-Jones, Bernie Mac, and Jeffrey Wright in Ocean's Twelve (2004)

George Clooney and Diane Salinger in Unbecoming Age (1992)

Brad Pitt, George Clooney, Don Cheadle, Matt Damon, Andy Garcia, Casey Affleck, Elliott Gould, Scott Caan, Bernie Mac, Carl Reiner, Eddie Jemison, and Shaobo Qin in Ocean's Thirteen (2007)