- He was a member of his high school's all-male acapella group, "Oriocos".
- Graduated from Columbia University.
- On the DVD for Gladiator (2000), he has a journal of his days on set.
- Enjoys traveling, photography, and the outdoors.
- Has appeared in two modern day adaptations of plays by William Shakespeare: Joss Whedon's Much Ado About Nothing (2012) and Michael Almereyda's Cymbeline (2014).
- As of 2022, he has appeared in two films that were nominated for the Best Picture Oscar: Gladiator (2000) and Mystic River (2003). Of those, Gladiator (2000) is a winner in the category.
- Brother of Eliza Clark.
- Spencer Treat Clark shares the same birthday as fellow Gladiator (2000) co-star Sven-Ole Thorsen. (Tigris).
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