| 11:00 PM | Local Programming |
| 11:30 PM | Dick Clark's New Year's Rockin' Eve With Ryan Seacrest 2010: The countdown to midnight and the drop of the crystal ball in Times Square. |
| 2:11 AM | Oprah Winfrey - Best of Oprah: Oprah's Most Jaw-Dropping Performances: Memorable performances, including appearances by Criss Angel and Terry Fator. |
| 3:10 AM | Who Wants to Be a Millionaire |
| 3:40 AM | ABC World News Now: Global news. |
| 4:30 AM | America This Morning: Breaking news. |
| 5:00 AM | Local Programming |
| 7:00 AM | Good Morning America: Chef Todd English; 2010 movie preview; predictions of trends in 2010. |
| 9:00 AM | Live With Regis and Kelly: In Miami, the annual Mom's Dream Come True special. |
| 10:00 AM | Rachael Ray: An Emmy- and Grammy-winning mystery taster; talking to children about sex. |
| 11:00 AM | Tournament of Roses Parade: The annual presentation takes place in Pasadena, Calif. |
| 1:00 PM | College Football - Capital One Bowl: LSU vs. Penn State : From Orlando, Fla. |
| 4:30 PM | Local Programming |
| 5:00 PM | College Football - Rose Bowl: Ohio State vs. Oregon : From Pasadena, Calif. |
| 8:30 PM | Better Off Ted - The Great Repression: A misunderstanding leads Sheila to falsely accuse Ted and Linda of sexual harassment. |
| 9:00 PM | Scrubs - Our New Girl-Bro: Turk tries to find a replacement best friend; Elliott offers some advice to exhausted Lucy. |
| 9:30 PM | Better Off Ted - Love Blurts: Veridian Dynamics tries to match employees based on their genetic compatibility. |
| 10:00 PM | 20/20: Investigative reporting. |
| 11:00 PM | Local Programming |
| 11:35 PM | Nightline: An update on the progress made by a woman and her son, who pledged to lose weight together. |