The music video has strong visual similarities to director Sophie Muller's 2010 music video for Sade's "Soldier of Love."
The dancing choreography was done by Fatima Robinson.
The song was featured in the soundtrack for the video game NBA 2K15.
The song was digitally released in Australia on April 14, 2014, and was serviced to contemporary hit radio in the United States on May 6 as the fifth overall single from the album.
According to the sheet music published at Musicnotes.com by Sony/ATV Music Publishing, "Love Runs Out" is written in the key of G minor with a moderate tempo of 120 beats per minute. Tedder's vocals span from D3 to D5 in the song.