The location for the coordinates of the target of the missile, N 38 54' by W 77 2', is on the grounds of the White House, Washington, D.C.
The title Rubicon is a reference to "crossing the Rubicon," which is a saying that means "a point of no return." Historically, it was the start of Caesar's civil war. This applies to Jaha and Murphy's hunt for the City of Light, Cage's decision to fire a missile at the Grounders, and Clarke's decision to not evacuate TonDC.
The name of the village that Cage launched the missile on was Tondc or Tondisi. It could have got its name from Washing"ton D.C.".
When Cage walks behind the desk of the President after his coup he moves a statuette of a Griffin a couple of centimeters. Clarke's last name is Griffin.