While promoting this movie in an interview on the National Public Radio program "Fresh Air," John Krasinski recalled that his first professional job as an actor in an extra in a Marshall's commercial in which the lead was Margo Martindale. While on that set, Krasinski got bumped up to "featured player," which meant that he got to interact with Martindale. Krasinski told the interviewer, "I didn't have lines. I think I was just the guy helping her pick out some very reasonably priced handbags."
While promoting this movie in an interview on the National Public Radio program "Fresh Air," John Krasinski recalled that while he was casting the roles, Richard Jenkins wrote him an email that said, "Love the script. If you get Margo [Martindale], I'll do it." Krasinski responded to Jenkins as though that was a joke, but Jenkins replied, "oh, I'm not kidding." "So I got Richard Jenkins. So as soon as Margo signed on Richard came with her, which is pretty phenomenal."
Filming took in various parts of Mississippi, including Jackson and a small town south of Jackson called Brookhaven. Filming locations in Brookhaven included the historic downtown area and the hospital.
Several actors in the movie have played characters with the similar first names in movies/series. John krasinski as John woodside in Aloha (2015), Anna Kendrick as Beca in pitch perfect (2012) and pitch perfect 2 (2015), Richard Jenkins as Don Fisk in What planet are you from? (2000) and Josh groban as Daniel in American Dad (2015) and Danny chase in the crazy ones (2014)