Jarrod Brom, one of the segment producers on the film, asked his bride-to-be if she would let the production prank their wedding on the condition that none of their friends and family know what was going on. She only had two stipulations: that the ceremony itself would not be affected, and that her dress would not be harmed.
A scene was shot where Bad Grandpa and his grandson visit the grave of deceased Jackass member Ryan Dunn but ultimately it was decided that the scene injected too much of a somber tone. Instead, the film ends with a dedication to Dunn in the closing credits.
Greg Harris spent a couple of hours in the biker bar prior to filming his scene where he takes delivery of his son. He used that time to essentially wind up the bikers and make them openly hostile towards him.
The drive-thru restaurant Billy and his grandfather stop by is called Sunrise Biscuit Kitchen. Sunrise Biscuit Kitchen is an actual store located at 1305 East Franklin Street in Chapel Hill, North Carolina; it is a very popular restaurant, famous for its biscuits and Southern fried chicken.
Many parts of the movie including the scenes in Kansas City and in Tennessee were shot in and around Charlotte, NC. The street signs can be seen with Charlotte's unmistakable "Queen City" crowns. Also many landmarks like the Penguin Drive In and Charlotte's unique skyline can be picked out along with Charlotte's public rail line transportation system, CATS.
During the gas station scene at the beginning of the film, a 2012 presidential election campaign sign can be seen in the convenient store window supporting Ron Paul. This gives a clue that the movie probably takes place between later 2011 to mid 2012.