Liz and the Task Force hunt for an elusive criminal who is destroying the world's precious treasures. Meanwhile, a surprise encounter leads Red toward a new business opportunity, as Tom investigates the bones in the suitcase.
Red provides intel on an international terrorist, putting the Task Force on a collision course with another unit from the CIA. Meanwhile, Red and Hawkins lay the groundwork for new business venture. Tom goes undercover in search of information.
While Cooper enlists Red on a case of personal importance, Ressler leads the Task Force to stop the resurgence of once-dormant murder-for-hire. Tom continues to investigate the suitcase despite a warning.
Red and the Task Force place Dembe undercover to infiltrate an international human smuggling organization, but when communication is lost, they must intervene. Meanwhile, Tom's investigation into the suitcase lands him in grave danger.