The hosts of Morning Glory talk about Francine "Baby Franny" Smith, using her married name.
Terry stops the "Baby Franny" chant by screaming "SHUT UP!!!" which brings total silence from the audience. He then says a meek "Thank you". This is a reference to the Cheech and Chong comedy song "Sister Mary Elephant" from their 1972 album Big Bambu.
The title is a reference to the National Treasure film series