Mindy needs Danny's help to assemble a bunk bed when she invites Gwen and her daughter to her flat for a sleepover. Elsewhere, Betsy, Shauna and Morgan uncover a secret while rooting through Danny's office.
Mindy wants to put some distance between Jamie and his clingy best friend Lucy, so she sets Lucy up on a Valentine's Day date with Danny, who is suffering from insomnia after his break-up with Jillian. Meanwhile, Morgan turns to Jeremy for advice on how to pick up women.
Mindy's friends throw a surprise party for her birthday, but due to the guest list and gifts she receives, Mindy throws a tantrum and leaves. Danny and Jeremy compete for the affections of Mindy's friend, Alex.
Mindy accidentally hooks up with a male prostitute, and tries to help him with his dream to become a singer. Danny and Alex's small gathering turns into a party when Mindy finds out Danny did not want to invite her.
During a trip to Santa Fe for a medical conference, Mindy visits her ex-boyfriend Josh, who wants to make amends for his deceit. Jeremy and Morgan clash while preparing for the conference. Danny receives a shock when his ex-wife shows up at the hospital.
Brendan and Duncan hire Morgan after Danny fires him for mailing a letter Danny wrote to his ex-wife. Mindy considers converting to Christianity for Casey. Danny, Morgan and Brendan get competitive when the hospital staff take part in a triathlon.
Mindy takes on a young medical student to pass on her wisdom to, and soon finds herself at a college frat party, where an encounter with a former flame has disastrous consequences. Meanwhile, Danny and Jeremy go to great lengths to try and get Morgan to leave Brendan and Duncan and return to work for them at the hospital.
Newly engaged Mindy returns from her volunteer mission in Haiti to New York for emergency surgery, only to find a new doctor has taken her place. Meanwhile, Danny and Christina's relationship continues to deteriorate.
Morgan sues Mindy for sexual harassment after she backs out of testing his theory that whoever sleeps with him finds the love of their life immediately afterwards. Danny wants Peter out of the practice.
Mindy begins dating Jason, an Arts and Culture writer. After Jason discerns that Mindy may not be cultured enough for him, she decides to invite him to Christina's art show, which features nude photos of Danny. Danny asks Cliff to figure out a way to shut down the exhibit.
When Danny tells Mindy she is too picky and judgemental of other people, she tries to prove him wrong by going on a date with her complete opposite. Jeremy is distressed when his dad visits the practice and takes an interest in Peter.
When Mindy tells Danny she has a crush, he thinks she's talking about him instead of Cliff, the lawyer (guest star Glenn Howerton). Meanwhile, Morgan (Ike Barinholtz) and Peter find Mindy's phone and respond to a text from Cliff, which starts off innocently, but escalates into something that may lead to unintended romantic consequences.
One of Danny's patients is a mommy blogger, so he invites her to write about Schulman & Associates on her website, only to find out that she is actually a white supremacist and paints the practice in a racist light. Desperate to control the situation, the team hires PR guru Priscilla (guest star Jenny Elfman), who begins to give Danny media training but ends up seducing him.
Mindy is surprised when her messed up ex-boyfriend, Josh, invites her to his wedding. She insists on taking a guy to the wedding so she won't look so miserable. Danny's brother, Richie, goes to NYC to visit his old brother.
Mindy plans an office Christmas party for the entire building, so she can spend more time with Cliff (guest star Glenn Howerton). However, things don't go Mindy's way when Brendan Deslaurier's date (guest star Maria Menounos) steals Mindy's thunder by performing a seductive "Santa Baby" dance for the party guests.