Mindy is a 30 something Ob/Gyn whose love life hits a snag after a messy break up with her long term boyfriend. After getting drunk and making a scene at his wedding, Mindy vows to put the past behind her, find the perfect man and get her life on track.
Mindy spends Thanksgiving at Gwen's house, where she runs into her former blind date Dennis and his new girlfriend. Elsehwere, Jeremy is introduced to Betsy's family, and Danny spends the evening alone at the hospital.
When Mindy encourages a teenager in her building to take things slow with her boyfriend, she is forced to reflect on her own relationship with Josh. Meanwhile Danny becomes concerned after receiving an anonymous complaint.