Jackson's suspicions about Mark and Lexie interfere with work.



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Episode cast overview, first billed only:


The doctors become nostalgic when George O'Malley's mother, Louise, returns to Seattle Grace for medical help after a botched surgery at a neighboring hospital; the residents are inspired by a medical miracle when they witness a harvested heart that continues to beat outside the body; a new pediatric fellow excites Arizona and makes Alex feel threatened; Jackson lets his suspicions about Mark and Lexie interfere with his work; and Henry and Teddy have their first marital fight when he expresses interest in pursuing medical school. Written by ABC Publicity

Plot Summary | Plot Synopsis


Drama | Romance





Release Date:

3 November 2011 (USA)  »

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Aspect Ratio:

16:9 HD
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Did You Know?


Every episode is named after a song. "Heart-Shaped Box" is a song by Nirvana. See more »


Dr. Meredith Grey: It's a little bit horrifying just how quickly everything can fall to crap. Sometimes, it takes a huge loss to remind you of what you care about the most. Sometimes, you find yourself becoming stronger as a result; wiser, better equipt to deal with the next big disaster that comes along. Sometimes, but, not always.
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Hold On
Performed by Mozella
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User Reviews

George's Mum is back!
27 February 2016 | by (United Kingdom) – See all my reviews

I know I say this every week but man I love Grey's Anatomy this season! Derek/Meredith being happy and positive about Zola! The whole heart-in-a-box storyline with Cristina. The funny scenes with the Chief/Cristina and Chief/Avery.

GEORGE'S MUM! I have been looking forward to this episode ever since I heard they were bringing her back. Nice move writers – it's about time we think about the fact that George actually existed. I know it's boring for the characters to dwell in the past, not to mention the fact it isolates viewers who may not have watched the series from the beginning, but it's about damn time that George was mentioned! George's Mum/Meredith <3. "George said you were the best". I love how happy George's Mum is to see Meredith. It's really endearing.

George's Mum/Callie+Arizona. "Dr Robbins". "Dr Torrez". Heee! I really liked Callie in this episode! Turns out my favourite Callie moments are basically all the times she's awkward about coming out to people! And the George's Mum/Callie moment later when Callie tells her about liking women and being married and having a baby and Mama O'Malley doesn't care about all of that, she just wants to see photos of the baby! That moment almost made me cry! It was just so touching! Bailey/Meredith and the George thing. The thing I love the most about this is how they tied in George's death with Meredith/trial thing and how Bailey explained why she's so mad at Meredith. That whole scene where they talk about George's death and how George was Bailey's favourite – top notch writing there! And that scene before where Meredith argues that she's good enough to do this surgery on George's Mum using Zola's custody as an example and then when Bailey advises her on what to wear <3 <3 <3. I am happy with this resolution to the Bailey/Meredith rift! Teddy/Henry <3 <3 <3 <3!!!! Wow, he slipped that one in there about going back to medical school!!!! I was almost as shocked as Teddy was! The author/Lexie. Loved it! Loved seeing Lexie get so into the book and good call making the time-travelling love story be a parallel to her own love life situation. Lexie generally was adorable in this episode.

Hee, Arizona loves Alex but she won't tell him to his face. She wants him to get the Peds fellowship and think he's amazing <3.

Alex's little bit about thinking of George made him think of Izzie <3 <3 <3. So glad we at least got to talk a bit about George and Izzie this episode. I really hated the way Alex spoke about George earlier but I thought his explanation about how thinking of George makes him think of Izzie was pretty sweet <3.


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