DIRECTOR_TRADEMARK(Robert Rodriguez): [Chingon]: The word "Chingon" across the back window of the armored Chevy El Camino they drive under the border, is not only vulgar Mexican slang for something or someone very tough and cool, but it's the name of Rodriguez's rock band. Music from Chingon has appeared in many of Rodriguez's films, including both Machetes.
In the chopper, when Machete is being transported along with Cereza, Zaror's ringtone on his cellphone is the opening notes and chords to Cancion Del Mariachi, a song from Desperado (1995), also a Robert Rodriguez film.
The film pokes fun at the Star Wars film franchise. Voz is a fan of Star Wars, and drives a landspeeder (with wheels), then dons a mask when his face is burned by Machete's flamethrower, and Machete and Voz are seen engaged in a lightsaber duel in the fake trailer "Machete Kills Again... In Space". Luz is at one point frozen in "carbonite".
At the end of the armored car chase scene, when Desdemona and her crew turn around and leave, a few notes from the "Spy Kids" theme music can be heard when Alexa PenaVega turns around and reveals her exposed back side.
The weapon that Voz is holding, when he is scorched by the flame thrower, is a Klingon bat'leth from the Star Trek Universe. William Sadler, who plays the Sheriff, played a secret agent in a few episodes of Star Trek: Deep Space Nine (1993), one of the series which prominently featured bat'leths.