As Dr. Eric Foreman tells Dr. Lisa Cuddy about House's latest hijinks, she sarcastically says, "Ma nishtana. . .All those years of medical school and you never went to a seder?. . It's 'Why is this night different from any other night'?" However, this is the beginning of the Four Questions, which the youngest possible person reads at the table at a Passover Seder. Transliterated, the First Question reads, "Ma nishtana halayla hazeh mikol haleilot?" In this context, Cuddy was saying that she was not surprised by whatever House was up to at the time.