Briarcliff, a former tuberculosis hospital, is now an insane asylum run by the Catholic church. It's 1964 and and the asylum houses some seriously disturbed individuals. The day to day administrator is in the hands of Sister Jude who works under the general supervision of Monsignor Timothy Howard. Her chief nemesis however is their in-house medical officer, Dr. Arthur Arden who is frequently seeing patients in the night - patients who die and are disposed of immediately. Briarcliff's latest patient is Kit Walker, aka Bloody Face, accused of murdering several young ...
A new doctor, Oliver Thredson, arrives at Briarcliff assigned by the courts to examine and report on Kit Walker. He's appalled by conditions he finds there and the fact that they still use electroshock to treat homosexuality. His view of how medicine is practiced is seemingly confirmed when a new patient arrives and Monsignor Howard decides that an exorcism is called for. In flashbacks, some of Sister Jude's life prior to becoming a nun is revealed. Lana continues to be a threat and Sister Jude convinces Dr. Adler to give her shock therapy in the hopes it will affect ...
It's Halloween and a major storm is expected in the area. Sister Jude decides to have a movie night in an attempt to calm the patients. She is being tormented by someone who knows about the auto accident she had before becoming a nun and sends her a newspaper clipping about the accident dated 1949. She turns to the bottle, a problem she had previously overcome. A possessed Sister Mary Eunice wreaks havoc in the asylum, killing one of the patients and makes sexual advances to an incredulous Dr. Adler. Shelley thinks the storm is the perfect cover to escape but is ...
A new arrival at Briarcliff Manor claims to be Anne Frank. She stabbed a man who made an anti-Semitic remark. When she sees Dr. Adler, she accuses him of being a doctor who worked at Auschwitz. Sister Jude is at first dismissive but soon begins to believe her. Adler gets help from a most unexpected source. Kit tells Grace what Dr. Adler has been doing to him and she in turn tells him why she is in the hospital. She was accused of butchering her father and her stepmother after her stepsister accused her of the crime. Lana tells Dr. Thredson about their attempted escape...
Convinced that Dr. Arden is a Nazi, Sister Jude hires a Nazi hunter, Goodman, to look into his past. He tells her of Operation Paperclip where American officials created false biographies for known Nazis and helped them relocate in the West. He tells her that SS officers have their blood type tattooed on their left arm. It all begins to go wrong when Anne Frank's husband shows up to collect his wife, who has had a breakdown since the birth of their baby. She's soon back at Briarcliff and Arden has his own plans for her. Kit is released from solitary but Grace is to go...
Monsignor Howard is called out to a local hospital to tend to the creature that was found in the schoolyard - and he obviously knows who she is. Sister Jude receives a call from Mr. Goodman confirming that Dr. Arden is a former Nazi who escaped at the end of the war. He needs just one more piece of evidence to make a final confirmation. Someone is out to protect the evil doctor however. Flashbacks reveal how he came to stay on at Briarcliff when it was taken over by the church. A woman is convinced her daughter is evil and desperately wants to leave her young daughter...
The angel of death descends upon Briarcliff Manor. Grace is found bleeding to death after her operation but is brought back from the abyss just as she was to receive the kiss of death. When Sister Mary Eunice accuses Dr. Arden of butchering the operation, he doesn't know what she talking about. Lana manages to escape from Bloody Face but gets a ride from someone who definitely has a thing about women. She soon finds herself back in the asylum. Sister Jude visits Mr. Goodman with Arden's fingerprints and finds him on the bathroom floor bleeding to death. He has barely ...
It's Christmas-time at Briarcliff Manor and with Sister Mary Eunice in charge, it's going to be a special holiday with a specially decorated tree. She entices Leigh Emerson, who killed 18 people from 5 families at Christmas two years ago, out of his solitary cell to attend. He had caused quite a commotion at Briarcliff the previous Christmas and she intends that he do the same this year. Lana realizes that Kit is also in the asylum and concludes that her own case has never been reported to the police. She tells Kit about Dr. Thredson. Sister Jude desperately wants to ...
Lana learns that she is pregnant and desperately wants to rid herself of the child. Sister Mary Eunice has other plans. Lana also tries to convince Kit that they must kill Thredson, who they've locked away. Monsignor Howard visits Sister Jude who is now an asylum inmate after her attack on Lee Emerson. Everything seems to line up against her but the Monsignor wonders if he is somehow at fault for her breakdown. Emerson has apparently had a religious conversion but he has a surprise for the Monsignor. Dr. Arden tries to make sense of his close encounter and finds some ...
Monsignor Howard is recovering from his wounds but Sister Mary Eunice continues to torment him. He decides there is only one way out for all of them. Sister Mary Eunice also has plans for Sister Jude, now known as Judy Martin - an extra powerful dose of electro-shock treatment which severely affects her memory in a particularly bizarre way. Dr. Thredson is hired as a staff doctor but Lana manages to stay one step ahead of him. Dr. Arden and Sister Mary Eunice share a destiny.