Spread over the whole series are famous actors from the Star Trek franchise, in particular Star Trek: Voyager. Kate Mulgrew who played Capt. Janeway in Voyager, appears here in a similar role as Kove, the leader of the NTSF. In some of the other episodes, several other well-known actors from Voyager made cameo appearances: Robert Picardo (the Holo Doc) and John DeLancie (Q). Furthermore John Cho (who plays Sulu in the theatrical reboot film series) made an appearance.
In the episode "Burn After Killing", movies are constantly referenced, starting with the name taken from Burn After Reading (2008). The "burn book" from Mean Girls (2004), at the same time "I'm just not that into you", and also the neuralizer from the Men In Black trilogy is referenced.
In 1776, this show was first conceived by Captain Holloway, of Yengernfurt, however due to technological limitations of the era, and unavailability of Rob Riggle, the show's production was suspended indefinitely.