Set on teaching his students the importance of getting a good night's rest, Adam conducts a sleep deprivation experiment at Finnegan. He uses his students as the test subjects, and challenges them to stay awake for the entire night, while hanging out in his class. As the night wears on, the group endures everything from exhaustion to hallucinations, while the various effects of sleep deprivation set in.
The producer of the popular science-based TV show, "Science Schmeince" arrives at Finnegan, looking to hire Adam as the show's new host. Adam agrees, seeing this as a great opportunity to spread his love of science to a broad audience. But, when the producer grows bored of Adam's science-y technobabble, he hires Derby as the zanier host of the show.
With Principal Tater constantly on Adam's back, Adam and Echo decide to calm his frustrations by finding him a woman. This proves more difficult than expected. But when Echo convinces Adam to match Tater up with Adam's mom, Rachel, everyone is happy -- everyone, except Adam.
When Adam can't get his class to stop talking, he assigns them oral presentations on the world's greatest discoveries. Through a series of flashbacks, our gang reenacts the events that led to the discovery of plutonium, the light bulb, fire, and more.
Having had his career ruined by Derby, Preston Pickles takes a job as Finnegan High's new shop teacher. But while no one else will believe him, Derby is convinced that Preston is trying to get rid of him. Derby must find a way to restart Preston's career as an infomercial pitchman, or face the wrath of the Derbinator 3000.
After Slab threatens Derby for tattling on him to Principal Tater, Derby fears retaliation and asks Tater for protection. Tater offers Derby a chance to pose as an exchange student from Britain, Simon. As Derby masquerades as Simon, Tater must convince Slab that Derby has actually moved away.
In hopes of getting Derby to stop acting up, Adam and Principal Tater decide he needs some responsibility. They suggest Derby run for Student Council President. However, when Derby does them one better by campaigning for School Superintendent, Adam and Tater must stop him from winning or risk losing their jobs.
Adam's old robot invention, ARTHUR, returns to Finnegan High and starts replacing staff and students with android copies. Adam and Echo must discover why everyone is acting so strangely, and stop Arthur's dastardly plan, before the entire school is overrun by robots.
The red carpet is rolled out for Finnegan's brightest stars to present their movies at the first annual Film Festival. With each student submitting a film, entries run the gamut from a sappy romantic comedy, to a 3D action thriller, to a Kung Fu extravaganza. May the best movie win!
A teenage girl, Brap, is accidentally transported from her home in the rainforest to Adam's classroom. She speaks no English, has superhuman strength, and believes she is an elephant! Impressed by her animal nature, Slab falls in love at first sight. But Brap only has eyes for Adam. While Echo and Adam try to help Brap fit in at Finnegan, Slab tries to win her affections.
Derby is spending all his time on the computer, playing "Pixel City," as his virtual alter-ego, Antoine Bolognese. Set on convincing Derby to rejoin the real world, Adam enters the game to track him down. But it won't be easy, since Derby has digitally recreated the entire Finnegan gang to serve and protect him.
Adam pretends to be a student at Finnegan High, so that he can join the Quiz Team and help Echo win a trophy. But when Slab takes Echo's spot on the team, Adam tries to force Slab off, so Echo can take his place.
When Adam finds out that Echo is obsessed with Dark Demon, a heavy metal musician that Adam knew in college, he tries to get his old friend to come to Finnegan High. But when Dark Demon refuses to make an appearance, Adam pretends to be the leather-clad rocker, and must perform at Echo's Save the Ferrets benefit.
After Adam secretly tweaks Echo's science fair project, she wins first prize. With everyone thinking Echo is a genius, she is instantly graduated from Finnegan and offered a full scholarship to Great Northern University. Now Adam, with the help of Derby and Slab, must crash a frat party and convince Echo to come back to Finnegan.
When Derby discovers his "free toy" is missing from his box of Cyclops Foods cereal, he and Adam set out to confront the massive corporation and demand what is rightfully theirs. Before long, Adam and Derby are face-to-face with the head of Cyclops Foods - an actual, one-eyed cyclops.
Adam's plan to take Echo to the school dance is foiled by Principal Tater. Determined to catch a notorious prankster, the "Gagmeister General," red-handed, Tater recruits Adam for a stakeout. Meanwhile, Ivy tries to get sympathy votes for Queen of the Dance by taking Derby as her date.
Adam's neural-imaging unit goes on the fritz, accidentally switching the gang's personalities. In order for Adam, Echo, Derby, Slab, Ivy, and Dang to return to their own bodies, they must work together to fix the machine before Principal Tater discovers their secret.
When Adam, Echo, Derby, Ivy, and Slab find themselves waiting outside Principal Tater's office together, they realize they're all in trouble for the same crime - wrecking Principal Tater's scooter. We hear their stories, which include hamsters being born, chickens being freed, and trips to Ireland.
With the paper airplane competition approaching, Finnegan High's Engineering Squad has no hope against rival Western High - that is, until Adam discovers Slab's untapped paper-folding genius. Adam must convince Slab to embrace his inner nerd and join the squad.
A dreamy new English teacher shows up at Finnegan High, teaching poetry, and gaining the attention of all the girls - particularly Echo. Adam becomes jealous and does everything in his power to prove that science is better than poetry.
The invisibility suit that Adam created goes missing, but is soon found in the hands of Derby, Slab, then Tater. Adam scolds them for using his suit irresponsibly, but then dons it himself to spy on Echo's romantic study date.
When Echo gets "nurse" on her career aptitude test, Adam attempts to get her to commit to his fantasy version of the job. But soon enough, Adam realizes she'll only commit if he commits to his result - alligator wrestler.
When Principal Tater forgets to pay the electricity bill at Finnegan High, he challenges the students to live without modern technology for an entire day. But when Slab's brute strength makes him most useful, a jealous Adam tries to impress Echo by being the manliest provider of all.
Adam follows Echo to the exotic country of Sanduras in the hopes of spending time with her, but he keeps getting pulled away by his guardian, Mrs. Byrne. Meanwhile, Derby and Slab travel to Sanduras by hot air balloon, and Tater and Dang search for a legendary beast: the Sasquawk.