While House is lying in bed playing a video game, a screen shot of the game is shown. It's the video game from the developer that House and his team treated in House M.D.: Epic Fail (2009) from Season Six.
House: Easy Rider auditions ended four decades ago. Referencing the 1969 counterculture movie where two hippie bikers, Wyatt and Billy, travel the U.S on their motorcycles looking for freedom. Wyatt's motorcycle has a gas tank decorated like an American flag, like the one that House looks at.