Three pupils of father Leo's prestigious Catholic high school St. Angelo's die from drug use at a party, hosted at home by classmate Caitlin Breyer. Jamie is able to save fourth user Alyson Duvitz's life by mouth to mouth. It seems an OD, then a bad designer drug. When known dealer Wayne Foster is arrested, after denunciation by school pusher Billy Romero, identified with some help from the archbishop after a talk with alumnus Frank, the lab shows the rest of his batch is clean. Danny must find a more personal motive, especially after his victim survives another attempt on her life, now by car.