In developing this series, producers Spike Brandt and Tony Cervone and producer/head writer Mitch Watson began with the original 1968-69 development art for Scooby Doo, Where Are You! (1969) by Joe Ruby and Ken Spears, which included information about the Scooby-Doo characters' ages, parents, and home/school life that never made it onscreen in the original series. In Ruby and Spears' original series bible, Fred and Shaggy are each 17 years old, Daphne is 16, and Velma is 15. For the purposes of this series, the kids were made roughly the same age: 16-17 in season 1, and 17-18 in season 2.
Unlike previous Scooby-Doo series, this series features intra-episode story arcs, including an overarching mystery that spans all 52 episodes. Some of the material for the series-long story arc was based on development work done on an unproduced animated series adaptation of The Goonies (1985)
At the time this series premiered on Cartoon Network, the Sally Corporation renamed the Scooby-Doo-themed amusement park rides "Boo Blasters on Boo Hill" at four particular Cedar Fair locations which were Carowinds, Kings Island, Kings Dominion, and Canada's Wonderland.
The trivia items below may give away important plot points.
In one of the earlier episodes, a girl says her father is the Creeper and the gang mentions they remember dealing with the Creeper. However, the Creeper was never on the current series and was only on one of the earlier series of the Scooby-Doo franchise.
In S1 E10, Jason, a love interest towards Velma and social outcast, was a potential suspect towards the attacks on Crystal Cove during this episode. Later, it is revealed to be his mother, getting revenge on the gang for disrespecting him earlier on in the episode. This is a potential nod towards Friday the 13th.
Both Gary Cole (Fred Jones, Sr.) and Tim Matheson (Brad Chiles), Fred's two dads on the show, played the Vice President on "West Wing." Tim Matheson played the first VP, John Hoynes, and Gary Cole played Hoynes' replacement Bob Russell.