A Providence team retrieving some valuable data is shot down over Kiev, which has been sealed off from the rest of the world. Rex, Six, and Bobo must enter the dome to retrieve the data, and encounter the inhabitants.
Researchers test a new way to eliminate nanites, but the results are not successful. Zag RS emerges and plans on using the method to destroy all the nanites. Rex must journey to a satellite to rescue Holiday and stop Zag RS.
Rex receives an urgent call from Circe. Abysus is in danger, and they desperately need Rex's help. Rex, Holiday and Six go to Abysus to find out what's going on. Rex balks when he realizes what will happen if he helps the Pack.
Van Kleiss steals Rex's nanites which powers up Van Kleiss and Rex powerless. Van Kleiss gains new abilities and attacks Providence. Meanwhile Rex tries to get his power back and finds something in his system.