Based on Agatha Christie's And Then There Were None, this episode sees nearly the whole of Quahog including the Griffins, Joe and Tom Tucker all invited to a party in their honour in a mysterious house. After the host is murdered, the guests must band together to try to figure out who the killer is. Yet, as more murders take place and more clues are revealed, the guests must decide who to turn into the police by morning. This episode was confirmed by Macfarlane to be a canon episode, the characters killed off in this episode have been officially terminated from the Family Guy series. Written by
Did You Know?
Because the show often ignores continuity if it would prevent funny and crazy stories, the producers took the unusual step after the Season 9 premiere of announcing that the events depicted were 100% part of the series canon--and that the deaths of characters such as Diane Simmons, Muriel Goldman, Derek Wilcox and James Woods would be part of the show's stories going forward. However, in Season 11 James Woods is magically returned to life, with the surreal explanation that he was revived via the life force of a teenage girl because that kind of re-animation is available to celebrities in the Family Guy universe. See more
In one scene Peter says that Joe and Priscilla are passed out, but in the scene where everyone are fighting Joe is conscious. He's behind the couch fighting with Dr. Hartman. See more
Can't we all just be happy she's dead?
References No Way Out