When Larry is getting fired for not going to college, Jack Strang (Rob Riggle's character) holds up his class ring and says "SMU Class of 1986. Solid gold. They weren't giving these things away." In 1986, SMU was given "The Death Penalty" by the NCAA for major infractions, including graduating students who had not earned an academic degree.
After being given the news that he was going to be cast as the husband of Julia Roberts' character, Bryan Cranston went on an accelerated workout and diet regiment. He also bleached his teeth white. Cranston claimed it was an attempt to come as close as possible to convince people that his character would be married to someone like Roberts, by having a younger looking character.
The last name of the lady at the bank is Gamelguard. This is a reference to That Thing You Do! (1996) (also with Tom Hanks). It is the same last name as the boy who last 'decently' kissed Faye (Liv Tyler). This is one of the last lines of the movie.
When the scooter "gang" rides into Larry's neighborhood for the yard sale, Lamar (Cedric the Entertainer's character) yells "We're being invaded!", which is a line from That Thing You Do! (1996). The line is first given by the character "Goofball" on the fictional set of "Weekend at Party Pier". Tom Hanks co-wrote, starred in, and directed That Thing You Do! (1996).