Jane and Maura find themselves submerged in the cutthroat, high-stakes world of competitive bass fishing when a tournament-leading fisherman is killed. At the same time, Frankie is paying the price after losing a bet.
Jane and Maura are called out to the BCU "Body Farm" (an academic research facility dedicated to the study of human decomposition) when a murder victim is found buried in a shallow grave among the research corpses. Angela has secrets she is keeping buried from Jane.
The crime lab loses one of their own. The team must set aside their personal feelings for the one they lost, & try to find out why their team member died & whether he/she was conducting illegal work on the side. Isles must accept that she cannot help with the investigation & Rizzoli has to adjust to working & solving the crime with another quick witted medical examiner.
When a 16-year-old girl is murdered and left in a cage, Jane and Maura must overcome the ethical dilemma of a psychiatrist and the stiff opposition of a fussy prosecutor in order to find the killer. Meanwhile, Jane has couch issues, and Frankie is seeing UFOs.
The murder of a college student takes an odd turn when Jane and Maura discover he had 32 girlfriends. Uncovering who killed him and why leads them into a world of app developers, virtual boyfriends and relationships built on lies. Meanwhile, Korsak finally introduces everyone to the new woman in his life.
When a dog trainer is found dead at home, her champion Rottweiler is the prime suspect. As the team investigates this unlikely killer, Maura has a peculiar interaction with Kent (recurring guest star ADAM SINCLAIR - 24: Live Another Day).
After a body turns up in Boston with links to a murder in Los Angeles, Jane and Maura pack up their sunscreen and hop on a plane. With the girls out of town, Angela and Korsak plan a double date with their respective dates, Kiki and Ron.
A security guard in a weed store, stops a robbery. The guard is shot and wounded as he kills one of the thieves. The police have lots of questions that go unanswered. Rizzoli & Isles search for the dead robbers accomplice. Later Rizzoli continues her efforts to protect Isles and Angela.
When a gun battle rages in a quiet neighborhood, leaving one dead, Jane and Maura are thrown into the secretive world of an Eastern European gang. Maura comes down with a fever while juggling work and play, and Angela and Kent prescribe several home remedies that have a surprising effect.
When a state trooper is killed in Maine, the getaway car is traced back to the mastermind of the attacks on Jane. The team must now unravel the mystery of the mastermind's obsession with Jane in order to keep her safe, and turn the hunter into the hunted.