A Fringe investigation is triggered when a patient at a mental institution undergoes an impromptu brain surgery that unexpectedly leaves his brain exposed. Despite the unthinkable circumstances, the patient's condition and sanity miraculously improves before the Fringe team arrives. While Agent Dunham and Peter scan surveillance tapes (and Walter enjoys his pudding), Olivia recognizes a familiar face as Thomas Jerome Newton, the leader of the "shape-shifters." As similar cases stack up, the Fringe team heads back to the lab to determine exactly how patients are being cured. Walter's brains are put to the test and William Bell resurfaces. Written by
Did You Know?
Another mystery substance, "Sirolomus", featured prominently in the episode, is derived from real-life drug Sirolimus, also known as Rapamycin, a substance discovered on the Easter Islands (Rapa Nui). It is a potent immunosuppressant used by transplant patients. More interestingly, it also seems to positively affect autism; however, its exact influence on brain cells and their metabolism is not yet fully researched. See more
And you're Dr. Walter Bishop?
Dr. Walter Bishop
Yes. And I'm perfectly sane.
Fringe Main Title Theme
Written by J.J. Abrams See more