When Echo discovers a file on Bennett Halverson, she comments that Bennett is "off-the-charts smart," adding, "I bet you could kill me with your brain." Bennett is played by Summer Glau, who in Joss Whedon's previous series, Firefly (2002), played River Tam, a psychic super-genius who once advised another character, "I can kill you with my brain." River's amygdala (part of the brain) was damaged by experiments, and Bennett says "I'd love to get a look at your [Caroline's] amygdala."
Topher and Ivy are programming the actives back to their original personalities in one scene. The active in the chair is Gary, played by Rick Fox who is in a relationship with the top billed actress on the show, Eliza Dushku.
The trivia item below may give away important plot points.
Clyde says the name Rossum is from a play and "Although technically you're not robots, it seemed to fit." In the 1920s Czechoslovakian play R. U. R. there are manufactured people, but those 'roboti' are biological constructs physically indistinguishable from humans. By the end of the play these biological slaves have developed into real people capable of free will, independent thought, and love. They ultimately replace the human race. This fits exactly.